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HSPCs display within-family homogeneity in differentiation and proliferation despite population hete...

HSPCs display within-family homogeneity in differentiation and proliferation despite population hete...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_86343bf28abc405f873426b6bf1f2021

HSPCs display within-family homogeneity in differentiation and proliferation despite population heterogeneity

About this item

Full title

HSPCs display within-family homogeneity in differentiation and proliferation despite population heterogeneity

Publisher

England: eLife Sciences Publications Ltd

Journal title

eLife, 2021-05, Vol.10

Language

English

Formats

Publication information

Publisher

England: eLife Sciences Publications Ltd

More information

Scope and Contents

Contents

High-throughput single-cell methods have uncovered substantial heterogeneity in the pool of hematopoietic stem and progenitor cells (HSPCs), but how much instruction is inherited by offspring from their heterogeneous ancestors remains unanswered. Using a method that enables simultaneous determination of common ancestor, division number, and differe...

Alternative Titles

Full title

HSPCs display within-family homogeneity in differentiation and proliferation despite population heterogeneity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_86343bf28abc405f873426b6bf1f2021

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_86343bf28abc405f873426b6bf1f2021

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.60624

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