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Development of a natural product optimization strategy for inhibitors against MraY, a promising anti...

Development of a natural product optimization strategy for inhibitors against MraY, a promising anti...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8640ff4ee8c741c084f0f712332ebe3b

Development of a natural product optimization strategy for inhibitors against MraY, a promising antibacterial target

About this item

Full title

Development of a natural product optimization strategy for inhibitors against MraY, a promising antibacterial target

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2024-06, Vol.15 (1), p.5085-15, Article 5085

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

MraY (phospho-
N
-acetylmuramoyl-pentapeptide-transferase) inhibitory natural products are attractive molecules as candidates for a new class of antibacterial agents to combat antimicrobial-resistant bacteria. Structural optimization of these natural products is required to improve their drug-like properties for therapeutic use. However, chem...

Alternative Titles

Full title

Development of a natural product optimization strategy for inhibitors against MraY, a promising antibacterial target

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_8640ff4ee8c741c084f0f712332ebe3b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8640ff4ee8c741c084f0f712332ebe3b

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-024-49484-7

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