DNA methylation presents distinct binding sites for human transcription factors
DNA methylation presents distinct binding sites for human transcription factors
About this item
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Author / Creator
Hu, Shaohui , Wan, Jun , Su, Yijing , Song, Qifeng , Zeng, Yaxue , Nguyen, Ha Nam , Shin, Jaehoon , Cox, Eric , Rho, Hee Sool , Woodard, Crystal , Xia, Shuli , Liu, Shuang , Lyu, Huibin , Ming, Guo-Li , Wade, Herschel , Song, Hongjun , Qian, Jiang and Zhu, Heng
Publisher
England: eLife Sciences Publications Ltd
Journal title
Language
English
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Publisher
England: eLife Sciences Publications Ltd
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Scope and Contents
Contents
DNA methylation, especially CpG methylation at promoter regions, has been generally considered as a potent epigenetic modification that prohibits transcription factor (TF) recruitment, resulting in transcription suppression. Here, we used a protein microarray-based approach to systematically survey the entire human TF family and found numerous puri...
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Full title
DNA methylation presents distinct binding sites for human transcription factors
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TN_cdi_doaj_primary_oai_doaj_org_article_8642ae0b23ca4623ab1a7419c8ee84c6
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8642ae0b23ca4623ab1a7419c8ee84c6
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.00726
