Externalized decondensed neutrophil chromatin occludes pancreatic ducts and drives pancreatitis
Externalized decondensed neutrophil chromatin occludes pancreatic ducts and drives pancreatitis
About this item
Full title
Author / Creator
Leppkes, Moritz , Maueröder, Christian , Hirth, Sebastian , Nowecki, Stefanie , Günther, Claudia , Billmeier, Ulrike , Paulus, Susanne , Biermann, Mona , Munoz, Luis E. , Hoffmann, Markus , Wildner, Dane , Croxford, Andrew L. , Waisman, Ari , Mowen, Kerri , Jenne, Dieter E. , Krenn, Veit , Mayerle, Julia , Lerch, Markus M. , Schett, Georg , Wirtz, Stefan , Neurath, Markus F. , Herrmann, Martin and Becker, Christoph
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Ductal occlusion has been postulated to precipitate focal pancreatic inflammation, while the nature of the primary occluding agents has remained elusive. Neutrophils make use of histone citrullination by peptidyl arginine deiminase-4 (PADI4) in contact to particulate agents to extrude decondensed chromatin as neutrophil extracellular traps (NETs)....
Alternative Titles
Full title
Externalized decondensed neutrophil chromatin occludes pancreatic ducts and drives pancreatitis
Authors, Artists and Contributors
Author / Creator
Maueröder, Christian
Hirth, Sebastian
Nowecki, Stefanie
Günther, Claudia
Billmeier, Ulrike
Paulus, Susanne
Biermann, Mona
Munoz, Luis E.
Hoffmann, Markus
Wildner, Dane
Croxford, Andrew L.
Waisman, Ari
Mowen, Kerri
Jenne, Dieter E.
Krenn, Veit
Mayerle, Julia
Lerch, Markus M.
Schett, Georg
Wirtz, Stefan
Neurath, Markus F.
Herrmann, Martin
Becker, Christoph
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_8649b3e8245b4fed8b30b9961760de6f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8649b3e8245b4fed8b30b9961760de6f
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms10973
