Cell-specific proteome analyses of human bone marrow reveal molecular features of age-dependent func...
Cell-specific proteome analyses of human bone marrow reveal molecular features of age-dependent functional decline
About this item
Full title
Author / Creator
Hennrich, Marco L. , Romanov, Natalie , Horn, Patrick , Jaeger, Samira , Eckstein, Volker , Steeples, Violetta , Ye, Fei , Ding, Ximing , Poisa-Beiro, Laura , Lai, Mang Ching , Lang, Benjamin , Boultwood, Jacqueline , Luft, Thomas , Zaugg, Judith B. , Pellagatti, Andrea , Bork, Peer , Aloy, Patrick , Gavin, Anne-Claude and Ho, Anthony D.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Diminishing potential to replace damaged tissues is a hallmark for ageing of somatic stem cells, but the mechanisms remain elusive. Here, we present proteome-wide atlases of age-associated alterations in human haematopoietic stem and progenitor cells (HPCs) and five other cell populations that constitute the bone marrow niche. For each, the abundan...
Alternative Titles
Full title
Cell-specific proteome analyses of human bone marrow reveal molecular features of age-dependent functional decline
Authors, Artists and Contributors
Author / Creator
Romanov, Natalie
Horn, Patrick
Jaeger, Samira
Eckstein, Volker
Steeples, Violetta
Ye, Fei
Ding, Ximing
Poisa-Beiro, Laura
Lai, Mang Ching
Lang, Benjamin
Boultwood, Jacqueline
Luft, Thomas
Zaugg, Judith B.
Pellagatti, Andrea
Bork, Peer
Aloy, Patrick
Gavin, Anne-Claude
Ho, Anthony D.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_86524845718d4cb59745f4c377ff0da5
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_86524845718d4cb59745f4c377ff0da5
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-06353-4
