Revisiting Proteasome Inhibitors: Molecular Underpinnings of Their Development, Mechanisms of Resist...
Revisiting Proteasome Inhibitors: Molecular Underpinnings of Their Development, Mechanisms of Resistance and Strategies to Overcome Anti-Cancer Drug Resistance
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Publisher
Switzerland: MDPI AG
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Language
English
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Switzerland: MDPI AG
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Contents
Proteasome inhibitors have shown relevant clinical activity in several hematological malignancies, namely in multiple myeloma and mantle cell lymphoma, improving patient outcomes such as survival and quality of life, when compared with other therapies. However, initial response to the therapy is a challenge as most patients show an innate resistanc...
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Full title
Revisiting Proteasome Inhibitors: Molecular Underpinnings of Their Development, Mechanisms of Resistance and Strategies to Overcome Anti-Cancer Drug Resistance
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TN_cdi_doaj_primary_oai_doaj_org_article_8685ca343ac848c2aa895341ddb40502
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8685ca343ac848c2aa895341ddb40502
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ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules27072201
