CDK2 Regulates HIV-1 Transcription by Phosphorylation of CDK9 on Serine 90
CDK2 Regulates HIV-1 Transcription by Phosphorylation of CDK9 on Serine 90
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
HIV-1 transcription is activated by the viral Tat protein that recruits host positive transcription elongation factor-b (P-TEFb) containing CDK9/cyclin T1 to the HIV-1 promoter. P-TEFb in the cells exists as a lower molecular weight CDK9/cyclin T1 dimer and a high molecular weight complex of 7SK RNA, CDK9/cyclin T1, HEXIM1 dimer and several additio...
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Full title
CDK2 Regulates HIV-1 Transcription by Phosphorylation of CDK9 on Serine 90
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TN_cdi_doaj_primary_oai_doaj_org_article_869d9b8910234b2db4a1782167c59398
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_869d9b8910234b2db4a1782167c59398
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ISSN
1742-4690
E-ISSN
1742-4690
DOI
10.1186/1742-4690-9-94
