EZH2-mediated macrophage-to-myofibroblast transition contributes to calcium oxalate crystal-induced...
EZH2-mediated macrophage-to-myofibroblast transition contributes to calcium oxalate crystal-induced kidney fibrosis
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Author / Creator
Xia, Yuqi , Ye, Zehua , Li, Bojun , Yan, Xinzhou , Yuan, Tianhui , Li, Lei , Song, Baofeng , Yu, Weimin , Rao, Ting , Ning, Jinzhuo , Zhu, Jiefu , Li, Xing , Mei, Shuqin , Mao, Zhiguo , Zhou, Xiangjun and Cheng, Fan
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Long-term nephrocalcinosis leads to kidney injury, fibrosis, and even chronic kidney disease (CKD). Macrophage-to-myofibroblast transition (MMT) has been identified as a new mechanism in CKD, however, the effect of MMT in calcium oxalate (CaOx)-induced kidney fibrosis remains unclear. In this study, abundant MMT cells are identified by immunofluore...
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Full title
EZH2-mediated macrophage-to-myofibroblast transition contributes to calcium oxalate crystal-induced kidney fibrosis
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TN_cdi_doaj_primary_oai_doaj_org_article_869ddf8f5ea44942bd95d118b00af0a3
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_869ddf8f5ea44942bd95d118b00af0a3
Other Identifiers
ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-025-07735-3
