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Ryanodine receptor dysfunction causes senescence and fibrosis in Duchenne dilated cardiomyopathy

Ryanodine receptor dysfunction causes senescence and fibrosis in Duchenne dilated cardiomyopathy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_86cf946208c7405482fdfb4f8454571b

Ryanodine receptor dysfunction causes senescence and fibrosis in Duchenne dilated cardiomyopathy

About this item

Full title

Ryanodine receptor dysfunction causes senescence and fibrosis in Duchenne dilated cardiomyopathy

Publisher

Germany: John Wiley & Sons, Inc

Journal title

Journal of Cachexia, Sarcopenia and Muscle, 2024-04, Vol.15 (2), p.536-551

Language

English

Formats

Publication information

Publisher

Germany: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Background
Duchenne muscular dystrophy (DMD) is an X‐linked disorder characterized by progressive muscle weakness due to the absence of functional dystrophin. DMD patients also develop dilated cardiomyopathy (DCM). We have previously shown that DMD (mdx) mice and a canine DMD model (GRMD) exhibit abnormal intracellular calcium (Ca2+) cycling rel...

Alternative Titles

Full title

Ryanodine receptor dysfunction causes senescence and fibrosis in Duchenne dilated cardiomyopathy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_86cf946208c7405482fdfb4f8454571b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_86cf946208c7405482fdfb4f8454571b

Other Identifiers

ISSN

2190-5991

E-ISSN

2190-6009

DOI

10.1002/jcsm.13411

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