The arginase 1/ornithine decarboxylase pathway suppresses HDAC3 to ameliorate the myeloid cell infla...
The arginase 1/ornithine decarboxylase pathway suppresses HDAC3 to ameliorate the myeloid cell inflammatory response: implications for retinal ischemic injury
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The enzyme arginase 1 (A1) hydrolyzes the amino acid arginine to form L-ornithine and urea. Ornithine is further converted to polyamines by the ornithine decarboxylase (ODC) enzyme. We previously reported that deletion of myeloid A1 in mice exacerbates retinal damage after ischemia/reperfusion (IR) injury. Furthermore, treatment with A1 protects ag...
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The arginase 1/ornithine decarboxylase pathway suppresses HDAC3 to ameliorate the myeloid cell inflammatory response: implications for retinal ischemic injury
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TN_cdi_doaj_primary_oai_doaj_org_article_86d72afde3964ebdb05e33acaea7cc03
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_86d72afde3964ebdb05e33acaea7cc03
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-023-06147-7
