Brevetoxin versus Brevenal Modulation of Human Nav1 Channels
Brevetoxin versus Brevenal Modulation of Human Nav1 Channels
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
Brevetoxins (PbTx) and brevenal are marine ladder-frame polyethers. PbTx binds to and activates voltage-gated sodium (Nav) channels in native tissues, whereas brevenal antagonizes these actions. However, the effects of PbTx and brevenal on recombinant Nav channel function have not been systematically analyzed. In this study, the PbTx-3 and brevenal...
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Full title
Brevetoxin versus Brevenal Modulation of Human Nav1 Channels
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TN_cdi_doaj_primary_oai_doaj_org_article_8708db02f00f4ce8a50d251d91f29066
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8708db02f00f4ce8a50d251d91f29066
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ISSN
1660-3397
E-ISSN
1660-3397
DOI
10.3390/md21070396
