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Non-invasive characterization of human bone marrow stimulation and reconstitution by cell-free messe...

Non-invasive characterization of human bone marrow stimulation and reconstitution by cell-free messe...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_87196fe47ad34f7e87daf12fccf54685

Non-invasive characterization of human bone marrow stimulation and reconstitution by cell-free messenger RNA sequencing

About this item

Full title

Non-invasive characterization of human bone marrow stimulation and reconstitution by cell-free messenger RNA sequencing

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2020-01, Vol.11 (1), p.400-11, Article 400

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Circulating cell-free mRNA (cf-mRNA) holds great promise as a non-invasive diagnostic biomarker. However, cf-mRNA composition and its potential clinical applications remain largely unexplored. Here we show, using Next Generation Sequencing-based profiling, that cf-mRNA is enriched in transcripts derived from the bone marrow compared to circulating...

Alternative Titles

Full title

Non-invasive characterization of human bone marrow stimulation and reconstitution by cell-free messenger RNA sequencing

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_87196fe47ad34f7e87daf12fccf54685

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_87196fe47ad34f7e87daf12fccf54685

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-019-14253-4

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