Disulfide-constrained peptide scaffolds enable a robust peptide-therapeutic discovery platform
Disulfide-constrained peptide scaffolds enable a robust peptide-therapeutic discovery platform
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Peptides present an alternative modality to immunoglobulin domains or small molecules for developing therapeutics to either agonize or antagonize cellular pathways associated with diseases. However, peptides often suffer from poor chemical and physical stability, limiting their therapeutic potential. Disulfide-constrained peptides (DCP) are natural...
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Full title
Disulfide-constrained peptide scaffolds enable a robust peptide-therapeutic discovery platform
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TN_cdi_doaj_primary_oai_doaj_org_article_875d8e01b17d45da81fe8d488c49ed25
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_875d8e01b17d45da81fe8d488c49ed25
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0300135
