Weight-bearing activity impairs nuclear membrane and genome integrity via YAP activation in plantar...
Weight-bearing activity impairs nuclear membrane and genome integrity via YAP activation in plantar melanoma
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Acral melanoma commonly occurs in areas that are not exposed to much sunlight, such as the sole of the foot. Little is known about risk factors and mutational processes of plantar acral melanoma. Nuclear envelope rupture during interphase contributes to genome instability in cancer. Here, we show that the nuclear and micronuclear membranes of melan...
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Weight-bearing activity impairs nuclear membrane and genome integrity via YAP activation in plantar melanoma
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TN_cdi_doaj_primary_oai_doaj_org_article_87601f1f43a54adea5e3790c852dc173
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_87601f1f43a54adea5e3790c852dc173
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-29925-x
