The Role and Regulation of the NKG2D/NKG2D Ligand System in Cancer
The Role and Regulation of the NKG2D/NKG2D Ligand System in Cancer
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Basel: MDPI AG
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Language
English
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Basel: MDPI AG
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The family of human NKG2D ligands (NKG2DL) consists of eight stress-induced molecules. Over 80% of human cancers express these ligands on the surface of tumour cells and/or associated stromal elements. In mice, NKG2D deficiency increases susceptibility to some types of cancer, implicating this system in immune surveillance for malignancy. However,...
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Full title
The Role and Regulation of the NKG2D/NKG2D Ligand System in Cancer
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TN_cdi_doaj_primary_oai_doaj_org_article_87790dab07ed47bda432c3da4c8ceb51
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_87790dab07ed47bda432c3da4c8ceb51
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ISSN
2079-7737
E-ISSN
2079-7737
DOI
10.3390/biology12081079
