Sunitinib treatment promotes metastasis of drug-resistant renal cell carcinoma via TFE3 signaling pa...
Sunitinib treatment promotes metastasis of drug-resistant renal cell carcinoma via TFE3 signaling pathway
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Author / Creator
Li, Luchao , Zhao, Shuo , Liu, Zhengfang , Zhang, Nianzhao , Pang, Shuo , Liu, Jikai , Liu, Cheng and Fan, Yidong
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Receptor tyrosine kinase (RTK) inhibitors, such as sunitinib and sorafenib, remain the first-line drugs for the treatment of mRCC. Acquired drug resistance and metastasis are the main causes of treatment failure. However, in the case of metastasis Renal Cell Cancer (mRCC), which showed a good response to sunitinib, we found that long-term treatment...
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Full title
Sunitinib treatment promotes metastasis of drug-resistant renal cell carcinoma via TFE3 signaling pathway
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TN_cdi_doaj_primary_oai_doaj_org_article_877926da828b4e209f40bf687d9b969d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_877926da828b4e209f40bf687d9b969d
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-021-03511-3
