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Optimizing a therapy for opiate use disorders: Characterizing ondansetron pharmacokinetics in blood...

Optimizing a therapy for opiate use disorders: Characterizing ondansetron pharmacokinetics in blood...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_878793b4463b4d988722f3c647db24b7

Optimizing a therapy for opiate use disorders: Characterizing ondansetron pharmacokinetics in blood and brain

About this item

Full title

Optimizing a therapy for opiate use disorders: Characterizing ondansetron pharmacokinetics in blood and brain

Publisher

United States: John Wiley & Sons, Inc

Journal title

Clinical and translational science, 2023-02, Vol.16 (2), p.216-223

Language

English

Formats

Publication information

Publisher

United States: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Administration of a widely used 5‐hydroxytryptamine receptor (5HT3AR) antagonist (ondansetron) potently inhibited the development of experimentally induced opioid dependence and withdrawal responses in mice and humans. However, in several studies examining withdrawal symptoms in subjects with chronic opioid use disorders (OUDs), ondansetron exhibit...

Alternative Titles

Full title

Optimizing a therapy for opiate use disorders: Characterizing ondansetron pharmacokinetics in blood and brain

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_878793b4463b4d988722f3c647db24b7

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_878793b4463b4d988722f3c647db24b7

Other Identifiers

ISSN

1752-8054

E-ISSN

1752-8062

DOI

10.1111/cts.13440

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