Distinct horizontal transfer mechanisms for type I and type V CRISPR-associated transposons
Distinct horizontal transfer mechanisms for type I and type V CRISPR-associated transposons
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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CASTs use both CRISPR-associated proteins and Tn7-family transposons for RNA-guided vertical and horizontal transmission. CASTs encode minimal CRISPR arrays but can’t acquire new spacers. Here, we report that CASTs can co-opt defense-associated CRISPR arrays for horizontal transmission. A bioinformatic analysis shows that CASTs co-occur with defens...
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Distinct horizontal transfer mechanisms for type I and type V CRISPR-associated transposons
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TN_cdi_doaj_primary_oai_doaj_org_article_87ad148d25754558b864c70a17ead820
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_87ad148d25754558b864c70a17ead820
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-50816-w