Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons
Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Despite critical roles of the hypothalamic arcuate neurons in controlling the growth and energy homeostasis, the gene regulatory network directing their development remains unclear. Here we report that the transcription factors Dlx1/2 and Otp coordinate the balanced generation of the two functionally related neurons in the hypothalamic arcuate nucl...
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Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons
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TN_cdi_doaj_primary_oai_doaj_org_article_87bb4bf21bac41069518ebbc205fec67
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_87bb4bf21bac41069518ebbc205fec67
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-04377-4