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Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons

Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_87bb4bf21bac41069518ebbc205fec67

Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons

About this item

Full title

Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2018-05, Vol.9 (1), p.2026-13, Article 2026

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Despite critical roles of the hypothalamic arcuate neurons in controlling the growth and energy homeostasis, the gene regulatory network directing their development remains unclear. Here we report that the transcription factors Dlx1/2 and Otp coordinate the balanced generation of the two functionally related neurons in the hypothalamic arcuate nucl...

Alternative Titles

Full title

Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_87bb4bf21bac41069518ebbc205fec67

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_87bb4bf21bac41069518ebbc205fec67

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-018-04377-4

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