Robust SNP-based prediction of rheumatoid arthritis through machine-learning-optimized polygenic ris...
Robust SNP-based prediction of rheumatoid arthritis through machine-learning-optimized polygenic risk score
About this item
Full title
Author / Creator
Lim, Ashley J. W. , Tyniana, C. Tera , Lim, Lee Jin , Tan, Justina Wei Lynn , Koh, Ee Tzun , Ang, Andrea Ee Ling , Chan, Grace Yin Lai , Chan, Madelynn Tsu-Li , Chia, Faith Li-Ann , Chng, Hiok Hee , Chua, Choon Guan , Howe, Hwee Siew , Koh, Li Wearn , Kong, Kok Ooi , Law, Weng Giap , Lee, Samuel Shang Ming , Lian, Tsui Yee , Lim, Xin Rong , Loh, Jess Mung Ee , Manghani, Mona , Tan, Sze-Chin , Teo, Claire Min-Li , Thong, Bernard Yu-Hor , Tjokrosaputro, Paula Permatasari , Xu, Chuanhui , Chong, Samuel S. , Khor, Chiea Chuen , Leong, Khai Pang , Lee, Caroline G. and TTSH Rheumatoid Arthritis Study Group
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
The popular statistics-based Genome-wide association studies (GWAS) have provided deep insights into the field of complex disorder genetics. However, its clinical applicability to predict disease/trait outcomes remains unclear as statistical models are not designed to make predictions. This study employs statistics-free machine-learning (ML)-optimi...
Alternative Titles
Full title
Robust SNP-based prediction of rheumatoid arthritis through machine-learning-optimized polygenic risk score
Authors, Artists and Contributors
Author / Creator
Tyniana, C. Tera
Lim, Lee Jin
Tan, Justina Wei Lynn
Koh, Ee Tzun
Ang, Andrea Ee Ling
Chan, Grace Yin Lai
Chan, Madelynn Tsu-Li
Chia, Faith Li-Ann
Chng, Hiok Hee
Chua, Choon Guan
Howe, Hwee Siew
Koh, Li Wearn
Kong, Kok Ooi
Law, Weng Giap
Lee, Samuel Shang Ming
Lian, Tsui Yee
Lim, Xin Rong
Loh, Jess Mung Ee
Manghani, Mona
Tan, Sze-Chin
Teo, Claire Min-Li
Thong, Bernard Yu-Hor
Tjokrosaputro, Paula Permatasari
Xu, Chuanhui
Chong, Samuel S.
Khor, Chiea Chuen
Leong, Khai Pang
Lee, Caroline G.
TTSH Rheumatoid Arthritis Study Group
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_87deb690648f4aca92310084051267ce
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_87deb690648f4aca92310084051267ce
Other Identifiers
ISSN
1479-5876
E-ISSN
1479-5876
DOI
10.1186/s12967-023-03939-5
