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Microsatellite instability at U2AF-binding polypyrimidic tract sites perturbs alternative splicing d...

Microsatellite instability at U2AF-binding polypyrimidic tract sites perturbs alternative splicing d...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_87efc7be65b6480c8bf4509103a6aab4

Microsatellite instability at U2AF-binding polypyrimidic tract sites perturbs alternative splicing during colorectal cancer initiation

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Microsatellite instability (MSI) due to mismatch repair deficiency (dMMR) is common in colorectal cancer (CRC). These cancers are associated with somatic coding events, but the noncoding pathophysiological impact of this genomic instability is yet poorly understood. Here, we perform an analysis of coding and noncoding MSI events at the different st...

Alternative Titles

Full title

Microsatellite instability at U2AF-binding polypyrimidic tract sites perturbs alternative splicing during colorectal cancer initiation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_87efc7be65b6480c8bf4509103a6aab4

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_87efc7be65b6480c8bf4509103a6aab4

Other Identifiers

ISSN

1474-760X,1474-7596,1465-6906

E-ISSN

1474-760X

DOI

10.1186/s13059-024-03340-5

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