Continuous flexibility analysis of SARS-CoV-2 spike prefusion structures
Continuous flexibility analysis of SARS-CoV-2 spike prefusion structures
About this item
Full title
Author / Creator
Melero, Roberto , Sorzano, Carlos Oscar S. , Foster, Brent , Vilas, José-Luis , Martínez, Marta , Marabini, Roberto , Ramírez-Aportela, Erney , Sanchez-Garcia, Ruben , Herreros, David , del Caño, Laura , Losana, Patricia , Fonseca-Reyna, Yunior C. , Conesa, Pablo , Wrapp, Daniel , Chacon, Pablo , McLellan, Jason S. , Tagare, Hemant D. and Carazo, Jose-Maria
Publisher
England: International Union of Crystallography
Journal title
Language
English
Formats
Publication information
Publisher
England: International Union of Crystallography
Subjects
More information
Scope and Contents
Contents
Using a new consensus-based image-processing approach together with principal component analysis, the flexibility and conformational dynamics of the SARS-CoV-2 spike in the prefusion state have been analysed. These studies revealed concerted motions involving the receptor-binding domain (RBD), N-terminal domain, and subdomains 1 and 2 around the pr...
Alternative Titles
Full title
Continuous flexibility analysis of SARS-CoV-2 spike prefusion structures
Authors, Artists and Contributors
Author / Creator
Sorzano, Carlos Oscar S.
Foster, Brent
Vilas, José-Luis
Martínez, Marta
Marabini, Roberto
Ramírez-Aportela, Erney
Sanchez-Garcia, Ruben
Herreros, David
del Caño, Laura
Losana, Patricia
Fonseca-Reyna, Yunior C.
Conesa, Pablo
Wrapp, Daniel
Chacon, Pablo
McLellan, Jason S.
Tagare, Hemant D.
Carazo, Jose-Maria
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_882a529feb224c03b4fe56e24b963384
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_882a529feb224c03b4fe56e24b963384
Other Identifiers
ISSN
2052-2525
E-ISSN
2052-2525
DOI
10.1107/S2052252520012725
