JMJD6 promotes melanoma carcinogenesis through regulation of the alternative splicing of PAK1, a key...
JMJD6 promotes melanoma carcinogenesis through regulation of the alternative splicing of PAK1, a key MAPK signaling component
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Author / Creator
Liu, Xujun , Si, Wenzhe , Liu, Xinhua , He, Lin , Ren, Jie , Yang, Ziran , Yang, Jianguo , Li, Wanjin , Liu, Shumeng , Pei, Fei , Yang, Xiaohan and Sun, Luyang
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Melanoma, originated from melanocytes located on the basal membrane of the epithelial tissue, is the most aggressive form of skin cancer that accounts for 75% of skin cancer-related death. Although it is believed that BRAF mutation and the mitogen-activated protein kinase (MAPK) pathway play critical roles in the pathogenesis of melanoma, how the M...
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Full title
JMJD6 promotes melanoma carcinogenesis through regulation of the alternative splicing of PAK1, a key MAPK signaling component
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_884853d979524cb0baaf96a8fa01dba1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_884853d979524cb0baaf96a8fa01dba1
Other Identifiers
ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/s12943-017-0744-2
