Neurofilament light and heterogeneity of disease progression in amyotrophic lateral sclerosis: devel...
Neurofilament light and heterogeneity of disease progression in amyotrophic lateral sclerosis: development and validation of a prediction model to improve interventional trials
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Interventional trials in amyotrophic lateral sclerosis (ALS) suffer from the heterogeneity of the disease as it considerably reduces statistical power. We asked if blood neurofilament light chains (NfL) could be used to anticipate disease progression and increase trial power.
In 125 patients with ALS from three independent prospective studies-on...
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Neurofilament light and heterogeneity of disease progression in amyotrophic lateral sclerosis: development and validation of a prediction model to improve interventional trials
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TN_cdi_doaj_primary_oai_doaj_org_article_885330fea1d344a7b200e9e29d421b8e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_885330fea1d344a7b200e9e29d421b8e
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ISSN
2047-9158
E-ISSN
2047-9158
DOI
10.1186/s40035-021-00257-y
