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Evaluation of the p53 pathway in polycystic ovarian syndrome pathogenesis and apoptosis enhancement...

Evaluation of the p53 pathway in polycystic ovarian syndrome pathogenesis and apoptosis enhancement...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_888a78fcb2c74d8fb1d7c48a98efec3a

Evaluation of the p53 pathway in polycystic ovarian syndrome pathogenesis and apoptosis enhancement in human granulosa cells through transcriptome data analysis

About this item

Full title

Evaluation of the p53 pathway in polycystic ovarian syndrome pathogenesis and apoptosis enhancement in human granulosa cells through transcriptome data analysis

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2023-07, Vol.13 (1), p.11648-11648, Article 11648

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The polycystic ovarian syndrome (PCOS) is closely associated with enhanced apoptosis of granulosa cells, which have a vital role in maturation of oocytes. p53 plays a critical role in the regulation of apoptosis and cell cycle arrest, metabolism and insulin resistance. The aim of this study was to investigate the impact of p53 pathway in enhancing...

Alternative Titles

Full title

Evaluation of the p53 pathway in polycystic ovarian syndrome pathogenesis and apoptosis enhancement in human granulosa cells through transcriptome data analysis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_888a78fcb2c74d8fb1d7c48a98efec3a

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_888a78fcb2c74d8fb1d7c48a98efec3a

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-023-38340-1

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