GPR180 is a component of TGFβ signalling that promotes thermogenic adipocyte function and mediates t...
GPR180 is a component of TGFβ signalling that promotes thermogenic adipocyte function and mediates the metabolic effects of the adipocyte-secreted factor CTHRC1
About this item
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Author / Creator
Balazova, Lucia , Balaz, Miroslav , Horvath, Carla , Horváth, Áron , Moser, Caroline , Kovanicova, Zuzana , Ghosh, Adhideb , Ghoshdastider, Umesh , Efthymiou, Vissarion , Kiehlmann, Elke , Sun, Wenfei , Dong, Hua , Ding, Lianggong , Amri, Ez-Zoubir , Nuutila, Pirjo , Virtanen, Kirsi A. , Niemi, Tarja , Ukropcova, Barbara , Ukropec, Jozef , Pelczar, Pawel , Lamla, Thorsten , Hamilton, Bradford , Neubauer, Heike and Wolfrum, Christian
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Activation of thermogenic brown and beige adipocytes is considered as a strategy to improve metabolic control. Here, we identify GPR180 as a receptor regulating brown and beige adipocyte function and whole-body glucose homeostasis, whose expression in humans is associated with improved metabolic control. We demonstrate that GPR180 is not a GPCR but...
Alternative Titles
Full title
GPR180 is a component of TGFβ signalling that promotes thermogenic adipocyte function and mediates the metabolic effects of the adipocyte-secreted factor CTHRC1
Authors, Artists and Contributors
Author / Creator
Balaz, Miroslav
Horvath, Carla
Horváth, Áron
Moser, Caroline
Kovanicova, Zuzana
Ghosh, Adhideb
Ghoshdastider, Umesh
Efthymiou, Vissarion
Kiehlmann, Elke
Sun, Wenfei
Dong, Hua
Ding, Lianggong
Amri, Ez-Zoubir
Nuutila, Pirjo
Virtanen, Kirsi A.
Niemi, Tarja
Ukropcova, Barbara
Ukropec, Jozef
Pelczar, Pawel
Lamla, Thorsten
Hamilton, Bradford
Neubauer, Heike
Wolfrum, Christian
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_88ee4530cad64964a1bb8fbac9b2b659
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_88ee4530cad64964a1bb8fbac9b2b659
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-27442-x
