A critical role of PRDM14 in human primordial germ cell fate revealed by inducible degrons
A critical role of PRDM14 in human primordial germ cell fate revealed by inducible degrons
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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PRDM14 is a crucial regulator of mouse primordial germ cells (mPGCs), epigenetic reprogramming and pluripotency, but its role in the evolutionarily divergent regulatory network of human PGCs (hPGCs) remains unclear. Besides, a previous knockdown study indicated that PRDM14 might be dispensable for human germ cell fate. Here, we decided to use induc...
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A critical role of PRDM14 in human primordial germ cell fate revealed by inducible degrons
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TN_cdi_doaj_primary_oai_doaj_org_article_89513bd8995b4d72af1095f2f4ba77c1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_89513bd8995b4d72af1095f2f4ba77c1
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2041-1723
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2041-1723
DOI
10.1038/s41467-020-15042-0
