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Loss of the TGFβ-activating integrin αvβ8 on dendritic cells protects mice from chronic intestinal p...

Loss of the TGFβ-activating integrin αvβ8 on dendritic cells protects mice from chronic intestinal p...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_896c37c39a0648e6bc82b41a1f9e89d0

Loss of the TGFβ-activating integrin αvβ8 on dendritic cells protects mice from chronic intestinal parasitic infection via control of type 2 immunity

About this item

Full title

Loss of the TGFβ-activating integrin αvβ8 on dendritic cells protects mice from chronic intestinal parasitic infection via control of type 2 immunity

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2013-10, Vol.9 (10), p.e1003675-e1003675

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Chronic intestinal parasite infection is a major global health problem, but mechanisms that promote chronicity are poorly understood. Here we describe a novel cellular and molecular pathway involved in the development of chronic intestinal parasite infection. We show that, early during development of chronic infection with the murine intestinal par...

Alternative Titles

Full title

Loss of the TGFβ-activating integrin αvβ8 on dendritic cells protects mice from chronic intestinal parasitic infection via control of type 2 immunity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_896c37c39a0648e6bc82b41a1f9e89d0

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_896c37c39a0648e6bc82b41a1f9e89d0

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1003675

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