Donor variability may mask dimethyl fumarate's effects on nuclear factor E2-related factor 2 in huma...
Donor variability may mask dimethyl fumarate's effects on nuclear factor E2-related factor 2 in human peripheral blood mononuclear cells
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Dimethyl fumarate (DMF) is an anti-inflammatory and antioxidant drug used to treat multiple sclerosis, but its mechanism(s) of action are not fully understood. In central nervous system (CNS) cells, DMF activates nuclear factor E2-related factor 2 (Nrf2), perhaps ameliorating oxidative stress-induced damage. However, it is not known whether DMF als...
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Full title
Donor variability may mask dimethyl fumarate's effects on nuclear factor E2-related factor 2 in human peripheral blood mononuclear cells
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TN_cdi_doaj_primary_oai_doaj_org_article_89a92a999d9b401eb7c96cb3495e061b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_89a92a999d9b401eb7c96cb3495e061b
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ISSN
1756-0500
E-ISSN
1756-0500
DOI
10.1186/s13104-017-2862-8
