A novel mucopolysaccharidosis type II mouse model with an iduronate-2-sulfatase-P88L mutation
A novel mucopolysaccharidosis type II mouse model with an iduronate-2-sulfatase-P88L mutation
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Mucopolysaccharidosis type II (MPS II) is a lysosomal storage disorder characterized by an accumulation of glycosaminoglycans (GAGs), including heparan sulfate, in the body. Major manifestations involve the central nerve system (CNS), skeletal deformation, and visceral manifestations. About 30% of MPS II is linked with an attenuated type of disease...
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A novel mucopolysaccharidosis type II mouse model with an iduronate-2-sulfatase-P88L mutation
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TN_cdi_doaj_primary_oai_doaj_org_article_89af4d5bd2e649eeb96d5d0a32f25537
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_89af4d5bd2e649eeb96d5d0a32f25537
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-023-34541-w
