METTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice
METTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice
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Author / Creator
Wang, Yuqin , Gao, Ming , Zhu, Fuxing , Li, Xinzhi , Yang, Ying , Yan, Qiuxin , Jia, Linna , Xie, Liwei and Chen, Zheng
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Contents
Brown adipose tissue (BAT) undergoes rapid postnatal development and then protects against cold and obesity into adulthood. However, the molecular mechanism that determines postnatal development and maturation of BAT is largely unknown. Here we show that METTL3 (a key RNA methyltransferase) expression increases significantly in interscapular brown...
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Full title
METTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice
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Author / Creator
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_89afae99cf9d4cde96210d96ab2ea0b3
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_89afae99cf9d4cde96210d96ab2ea0b3
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-15488-2
