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Adaptation of hepatitis C virus to interferon lambda polymorphism across multiple viral genotypes

Adaptation of hepatitis C virus to interferon lambda polymorphism across multiple viral genotypes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_89cbeb30939249ecbe21013f4a0de48c

Adaptation of hepatitis C virus to interferon lambda polymorphism across multiple viral genotypes

About this item

Full title

Adaptation of hepatitis C virus to interferon lambda polymorphism across multiple viral genotypes

Publisher

England: eLife Sciences Publications Ltd

Journal title

eLife, 2019-09, Vol.8

Language

English

Formats

Publication information

Publisher

England: eLife Sciences Publications Ltd

More information

Scope and Contents

Contents

Genetic polymorphism in the interferon lambda (IFN-λ) region is associated with spontaneous clearance of hepatitis C virus (HCV) infection and response to interferon-based treatment. Here, we evaluate associations between IFN-λ polymorphism and HCV variation in 8729 patients (Europeans 77%, Asians 13%, Africans 8%) infected with various viral genot...

Alternative Titles

Full title

Adaptation of hepatitis C virus to interferon lambda polymorphism across multiple viral genotypes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_89cbeb30939249ecbe21013f4a0de48c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_89cbeb30939249ecbe21013f4a0de48c

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.42542

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