Enhancement of adenosine A2A signaling improves dopamine D2 receptor antagonist-induced dyskinesia v...
Enhancement of adenosine A2A signaling improves dopamine D2 receptor antagonist-induced dyskinesia via β-arrestin signaling
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Frontiers Media S.A
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Language
English
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Frontiers Media S.A
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Contents
Repeated administration of dopamine D
2
receptor (D2R) antagonists, which is the treatment for psychosis, often causes tardive dyskinesia (TD). Despite notable clinical demand, effective treatment for TD has not been established yet. The neural mechanism involving the hyperinhibition of indirect pathway medium spiny neurons (iMSNs) in the str...
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Full title
Enhancement of adenosine A2A signaling improves dopamine D2 receptor antagonist-induced dyskinesia via β-arrestin signaling
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TN_cdi_doaj_primary_oai_doaj_org_article_89e64b3fef674dcab50c14b9ceb32b0b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_89e64b3fef674dcab50c14b9ceb32b0b
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ISSN
1662-453X,1662-4548
E-ISSN
1662-453X
DOI
10.3389/fnins.2022.1082375
