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Mast cells are major contributors to the pathophysiology of Graves’ Ophthalmopathy (GO)

Mast cells are major contributors to the pathophysiology of Graves’ Ophthalmopathy (GO)

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8a21e2f242b646e5b258a73568e5ed53

Mast cells are major contributors to the pathophysiology of Graves’ Ophthalmopathy (GO)

About this item

Full title

Mast cells are major contributors to the pathophysiology of Graves’ Ophthalmopathy (GO)

Publisher

London: BioMed Central

Journal title

Journal of translational medicine, 2010-11, Vol.8 (S1), p.P22-P22, Article P22

Language

English

Formats

Publication information

Publisher

London: BioMed Central

Subjects

More information

Scope and Contents

Contents

Conclusion Mast cells are important in the pathophysiology of GO, as their numbers are increased in GO orbital tissue and their products histamine and tryptase stimulate cytokine and hyaluronan production as well as orbital fibroblast proliferation. [...] mast cells contribute to the orbital inflammation and tissue expansion typical for GO.

Alternative Titles

Full title

Mast cells are major contributors to the pathophysiology of Graves’ Ophthalmopathy (GO)

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_8a21e2f242b646e5b258a73568e5ed53

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8a21e2f242b646e5b258a73568e5ed53

Other Identifiers

ISSN

1479-5876

E-ISSN

1479-5876

DOI

10.1186/1479-5876-8-S1-P22

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