MyD88 inhibitor TJ-M2010-5 alleviates spleen impairment and inflammation by inhibiting the PI3K/miR-...
MyD88 inhibitor TJ-M2010-5 alleviates spleen impairment and inflammation by inhibiting the PI3K/miR-136-5p/AKT3 pathway in the early infection of Trichinella spiralis
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England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Trichinella spiralis
(
T. spiralis
) has been reported to induce inflammation, which can cause immune system dysregulation. Myeloid differentiation primary response gene 88 (MyD88) is implicated in inflammation signalling pathways. TJ-M2010-5 is a novel MyD88 inhibitor with remarkable protective effects against several diseases. However, t...
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Full title
MyD88 inhibitor TJ-M2010-5 alleviates spleen impairment and inflammation by inhibiting the PI3K/miR-136-5p/AKT3 pathway in the early infection of Trichinella spiralis
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TN_cdi_doaj_primary_oai_doaj_org_article_8a28a2ea79b8456b84af7157fa2c9bb0
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8a28a2ea79b8456b84af7157fa2c9bb0
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ISSN
1297-9716,0928-4249
E-ISSN
1297-9716
DOI
10.1186/s13567-025-01459-2
