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Prevention of noise-induced hearing loss by calpain inhibitor MDL-28170 is associated with upregulat...

Prevention of noise-induced hearing loss by calpain inhibitor MDL-28170 is associated with upregulat...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8a4fc7ea3d4c40f0bbc15de3632b6fcd

Prevention of noise-induced hearing loss by calpain inhibitor MDL-28170 is associated with upregulation of PI3K/Akt survival signaling pathway

About this item

Full title

Prevention of noise-induced hearing loss by calpain inhibitor MDL-28170 is associated with upregulation of PI3K/Akt survival signaling pathway

Publisher

Switzerland: Frontiers Research Foundation

Journal title

Frontiers in cellular neuroscience, 2023-07, Vol.17, p.1199656

Language

English

Formats

Publication information

Publisher

Switzerland: Frontiers Research Foundation

More information

Scope and Contents

Contents

Noise-induced calcium overload in sensory hair cells has been well documented as an early step in the pathogenesis of noise-induced hearing loss (NIHL). Alterations in cellular calcium homeostasis mediate a series of cellular events, including activation of calcium-dependent protein kinases and phosphatases. Using cell-membrane- and blood-brain-bar...

Alternative Titles

Full title

Prevention of noise-induced hearing loss by calpain inhibitor MDL-28170 is associated with upregulation of PI3K/Akt survival signaling pathway

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_8a4fc7ea3d4c40f0bbc15de3632b6fcd

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8a4fc7ea3d4c40f0bbc15de3632b6fcd

Other Identifiers

ISSN

1662-5102

E-ISSN

1662-5102

DOI

10.3389/fncel.2023.1199656

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