A human induced pluripotent stem cell‐derived cortical neuron human‐on‐a chip system to study Aβ42 a...
A human induced pluripotent stem cell‐derived cortical neuron human‐on‐a chip system to study Aβ42 and tau‐induced pathophysiological effects on long‐term potentiation
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Publisher
Hoboken: John Wiley & Sons, Inc
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Language
English
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Publisher
Hoboken: John Wiley & Sons, Inc
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Introduction
The quest to identify an effective therapeutic strategy for neurodegenerative diseases, such as mild congitive impairment (MCI) and Alzheimer's disease (AD), suffers from the lack of good human‐based models. Animals represent the most common models used in basic research and drug discovery studies. However, safe and effective compou...
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A human induced pluripotent stem cell‐derived cortical neuron human‐on‐a chip system to study Aβ42 and tau‐induced pathophysiological effects on long‐term potentiation
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TN_cdi_doaj_primary_oai_doaj_org_article_8ab4da9401284f14b3fea7a3aaf3f165
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8ab4da9401284f14b3fea7a3aaf3f165
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ISSN
2352-8737
E-ISSN
2352-8737
DOI
10.1002/trc2.12029