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A human induced pluripotent stem cell‐derived cortical neuron human‐on‐a chip system to study Aβ42 a...

A human induced pluripotent stem cell‐derived cortical neuron human‐on‐a chip system to study Aβ42 a...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8ab4da9401284f14b3fea7a3aaf3f165

A human induced pluripotent stem cell‐derived cortical neuron human‐on‐a chip system to study Aβ42 and tau‐induced pathophysiological effects on long‐term potentiation

About this item

Full title

A human induced pluripotent stem cell‐derived cortical neuron human‐on‐a chip system to study Aβ42 and tau‐induced pathophysiological effects on long‐term potentiation

Publisher

Hoboken: John Wiley & Sons, Inc

Journal title

Alzheimer's & dementia : translational research & clinical interventions, 2020, Vol.6 (1), p.n/a

Language

English

Formats

Publication information

Publisher

Hoboken: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Introduction
The quest to identify an effective therapeutic strategy for neurodegenerative diseases, such as mild congitive impairment (MCI) and Alzheimer's disease (AD), suffers from the lack of good human‐based models. Animals represent the most common models used in basic research and drug discovery studies. However, safe and effective compou...

Alternative Titles

Full title

A human induced pluripotent stem cell‐derived cortical neuron human‐on‐a chip system to study Aβ42 and tau‐induced pathophysiological effects on long‐term potentiation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_8ab4da9401284f14b3fea7a3aaf3f165

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8ab4da9401284f14b3fea7a3aaf3f165

Other Identifiers

ISSN

2352-8737

E-ISSN

2352-8737

DOI

10.1002/trc2.12029

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