DNA damage-induced transcription stress triggers the genome-wide degradation of promoter-bound Pol I...
DNA damage-induced transcription stress triggers the genome-wide degradation of promoter-bound Pol II
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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The precise regulation of RNA Polymerase II (Pol II) transcription after genotoxic stress is crucial for proper execution of the DNA damage-induced stress response. While stalling of Pol II on transcription-blocking lesions (TBLs) blocks transcript elongation and initiates DNA repair in cis, TBLs additionally elicit a response in trans that regulat...
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DNA damage-induced transcription stress triggers the genome-wide degradation of promoter-bound Pol II
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TN_cdi_doaj_primary_oai_doaj_org_article_8ae0ddc4ec8841d3a8a8b7435095a252
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8ae0ddc4ec8841d3a8a8b7435095a252
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-31329-w
