Exosomes taken up by neurons hijack the endosomal pathway to spread to interconnected neurons
Exosomes taken up by neurons hijack the endosomal pathway to spread to interconnected neurons
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Publisher
England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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In Alzheimer disease and related disorders, the microtubule-associated protein tau aggregates and forms cytoplasmic lesions that impair neuronal physiology at many levels. In addition to affecting the host neuron, tau aggregates also spread to neighboring, recipient cells where the misfolded tau aggregates, in a manner similar to prions, actively c...
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Full title
Exosomes taken up by neurons hijack the endosomal pathway to spread to interconnected neurons
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TN_cdi_doaj_primary_oai_doaj_org_article_8af45514d2f84163b48c53b0d75ee398
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8af45514d2f84163b48c53b0d75ee398
Other Identifiers
ISSN
2051-5960
E-ISSN
2051-5960
DOI
10.1186/s40478-018-0514-4
