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Gating mechanism of elongating β-ketoacyl-ACP synthases

Gating mechanism of elongating β-ketoacyl-ACP synthases

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8b2f324577e8467b8bb69a969b0ffd83

Gating mechanism of elongating β-ketoacyl-ACP synthases

About this item

Full title

Gating mechanism of elongating β-ketoacyl-ACP synthases

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2020-04, Vol.11 (1), p.1727-15, Article 1727

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Carbon-carbon bond forming reactions are essential transformations in natural product biosynthesis. During de novo fatty acid and polyketide biosynthesis, β-ketoacyl-acyl carrier protein (ACP) synthases (KS), catalyze this process via a decarboxylative Claisen-like condensation reaction. KSs must recognize multiple chemically distinct ACPs and chor...

Alternative Titles

Full title

Gating mechanism of elongating β-ketoacyl-ACP synthases

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_8b2f324577e8467b8bb69a969b0ffd83

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8b2f324577e8467b8bb69a969b0ffd83

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-020-15455-x

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