Gating mechanism of elongating β-ketoacyl-ACP synthases
Gating mechanism of elongating β-ketoacyl-ACP synthases
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Carbon-carbon bond forming reactions are essential transformations in natural product biosynthesis. During de novo fatty acid and polyketide biosynthesis, β-ketoacyl-acyl carrier protein (ACP) synthases (KS), catalyze this process via a decarboxylative Claisen-like condensation reaction. KSs must recognize multiple chemically distinct ACPs and chor...
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Gating mechanism of elongating β-ketoacyl-ACP synthases
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TN_cdi_doaj_primary_oai_doaj_org_article_8b2f324577e8467b8bb69a969b0ffd83
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8b2f324577e8467b8bb69a969b0ffd83
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-15455-x