Antibodies utilizing VL6-57 light chains target a convergent cryptic epitope on SARS-CoV-2 spike pro...
Antibodies utilizing VL6-57 light chains target a convergent cryptic epitope on SARS-CoV-2 spike protein and potentially drive the genesis of Omicron variants
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Author / Creator
Yan, Qihong , Gao, Xijie , Liu, Banghui , Hou, Ruitian , He, Ping , Ma, Yong , Zhang, Yudi , Zhang, Yanjun , Li, Zimu , Chen, Qiuluan , Wang, Jingjing , Huang, Xiaohan , Liang, Huan , Zheng, Huiran , Yao, Yichen , Chen, Xianying , Niu, Xuefeng , He, Jun , Chen, Ling , Zhao, Jincun and Xiong, Xiaoli
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Continued evolution of SARS-CoV-2 generates variants to challenge antibody immunity established by infection and vaccination. A connection between population immunity and genesis of virus variants has long been suggested but its molecular basis remains poorly understood. Here, we identify a class of SARS-CoV-2 neutralizing public antibodies defined...
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Full title
Antibodies utilizing VL6-57 light chains target a convergent cryptic epitope on SARS-CoV-2 spike protein and potentially drive the genesis of Omicron variants
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_8b39b6be46864368911fc0a43d056643
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8b39b6be46864368911fc0a43d056643
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-51770-3
