LIFR inhibition enhances the therapeutic efficacy of HDAC inhibitors in triple negative breast cance...
LIFR inhibition enhances the therapeutic efficacy of HDAC inhibitors in triple negative breast cancer
About this item
Full title
Author / Creator
Li, Mengxing , Viswanadhapalli, Suryavathi , Santhamma, Bindu , Pratap, Uday P. , Luo, Yiliao , Liu, Junhao , Altwegg, Kristin A. , Tang, Weiwei , Liu, Zexuan , Li, Xiaonan , Ebrahimi, Behnam , Yan, Hui , Zou, Yi , Konda, Swapna , Sareddy, Gangadhara R. , Xu, Zhenming , Chen, Yidong , Rao, Manjeet K. , Brenner, Andrew J. , Kaklamani, Virginia G. , Tekmal, Rajeshwar R. , Ahmed, Gulzar , Raj, Ganesh V. , Nickisch, Klaus J. , Nair, Hareesh B. and Vadlamudi, Ratna K.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Histone deacetylase inhibitors (HDACi) are identified as novel therapeutic agents, however, recent clinical studies suggested that they are marginally effective in treating triple negative breast cancer (TNBC). Here, we show that first-in-class Leukemia Inhibitory Factor Receptor (LIFRα) inhibitor EC359 could enhance the therapeutic efficacy of HDA...
Alternative Titles
Full title
LIFR inhibition enhances the therapeutic efficacy of HDAC inhibitors in triple negative breast cancer
Authors, Artists and Contributors
Author / Creator
Viswanadhapalli, Suryavathi
Santhamma, Bindu
Pratap, Uday P.
Luo, Yiliao
Liu, Junhao
Altwegg, Kristin A.
Tang, Weiwei
Liu, Zexuan
Li, Xiaonan
Ebrahimi, Behnam
Yan, Hui
Zou, Yi
Konda, Swapna
Sareddy, Gangadhara R.
Xu, Zhenming
Chen, Yidong
Rao, Manjeet K.
Brenner, Andrew J.
Kaklamani, Virginia G.
Tekmal, Rajeshwar R.
Ahmed, Gulzar
Raj, Ganesh V.
Nickisch, Klaus J.
Nair, Hareesh B.
Vadlamudi, Ratna K.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_8b39ff553a7a47e7a5a926087847574b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8b39ff553a7a47e7a5a926087847574b
Other Identifiers
ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-021-02741-7
