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Spontaneous shaker rat mutant – a new model for X-linked tremor/ataxia

Spontaneous shaker rat mutant – a new model for X-linked tremor/ataxia

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8b694b27a1ca480087bfad92ee4ec7f8

Spontaneous shaker rat mutant – a new model for X-linked tremor/ataxia

About this item

Full title

Spontaneous shaker rat mutant – a new model for X-linked tremor/ataxia

Publisher

England: The Company of Biologists Ltd

Journal title

Disease models & mechanisms, 2016-05, Vol.9 (5), p.553-562

Language

English

Formats

Publication information

Publisher

England: The Company of Biologists Ltd

More information

Scope and Contents

Contents

The shaker rat is an X-linked recessive spontaneous model of progressive Purkinje cell (PC) degeneration exhibiting a shaking ataxia and wide stance. Generation of Wistar Furth (WF)/Brown Norwegian (BN) F1 hybrids and genetic mapping of F2 sib-sib offspring using polymorphic markers narrowed the candidate gene region to 26 Mbp denoted by the last r...

Alternative Titles

Full title

Spontaneous shaker rat mutant – a new model for X-linked tremor/ataxia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_8b694b27a1ca480087bfad92ee4ec7f8

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8b694b27a1ca480087bfad92ee4ec7f8

Other Identifiers

ISSN

1754-8403

E-ISSN

1754-8411

DOI

10.1242/dmm.022848

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