Novel [18F]-labeled thiol for the labeling of Dha- or maleimide-containing biomolecules
Novel [18F]-labeled thiol for the labeling of Dha- or maleimide-containing biomolecules
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Cham: Springer International Publishing
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Language
English
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Cham: Springer International Publishing
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Background
Prosthetic approach for the radiolabeling of biologics with fluorine-18 is a robust strategy and has been employed for many years. It requires fast, biocompatible and selective reactions suited to these fragile molecules. Michael addition of a nucleophilic thiol moiety on α,β-unsaturated carbonyl entities is an interesting compromise...
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Full title
Novel [18F]-labeled thiol for the labeling of Dha- or maleimide-containing biomolecules
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TN_cdi_doaj_primary_oai_doaj_org_article_8bd9af06b2b940d7a72aed3af45681d4
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8bd9af06b2b940d7a72aed3af45681d4
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ISSN
2365-421X
E-ISSN
2365-421X
DOI
10.1186/s41181-022-00160-5
