Structural and dynamic mechanisms of GABAA receptor modulators with opposing activities
Structural and dynamic mechanisms of GABAA receptor modulators with opposing activities
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
γ-Aminobutyric acid type A (GABA
A
) receptors are pentameric ligand-gated ion channels abundant in the central nervous system and are prolific drug targets for treating anxiety, sleep disorders and epilepsy. Diverse small molecules exert a spectrum of effects on γ-aminobutyric acid type A (GABA
A
) receptors by acting at the classical...
Alternative Titles
Full title
Structural and dynamic mechanisms of GABAA receptor modulators with opposing activities
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_8bdf68ac057b4f82838f0620509d6a37
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8bdf68ac057b4f82838f0620509d6a37
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-32212-4
