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Common biological phenotypes characterize the acquisition of platinum-resistance in epithelial ovari...

Common biological phenotypes characterize the acquisition of platinum-resistance in epithelial ovari...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8bf1a13f3ec742d7ba5ce35739f9999f

Common biological phenotypes characterize the acquisition of platinum-resistance in epithelial ovarian cancer cells

About this item

Full title

Common biological phenotypes characterize the acquisition of platinum-resistance in epithelial ovarian cancer cells

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2017-08, Vol.7 (1), p.7104-12, Article 7104

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Standard of care for Epithelial Ovarian Cancer (EOC) patients relies on platinum-based therapy. However, acquired resistance to platinum occurs frequently and predicts poor prognosis. To understand the mechanisms underlying acquired platinum-resistance, we have generated and characterized three platinum-resistant isogenic EOC cell lines. Resistant...

Alternative Titles

Full title

Common biological phenotypes characterize the acquisition of platinum-resistance in epithelial ovarian cancer cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_8bf1a13f3ec742d7ba5ce35739f9999f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8bf1a13f3ec742d7ba5ce35739f9999f

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-017-07005-1

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