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Improving Bone Health by Optimizing the Anabolic Action of Wnt Inhibitor Multitargeting

Improving Bone Health by Optimizing the Anabolic Action of Wnt Inhibitor Multitargeting

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8bf70de22fa94fbbae843dd1f34ce38c

Improving Bone Health by Optimizing the Anabolic Action of Wnt Inhibitor Multitargeting

About this item

Full title

Improving Bone Health by Optimizing the Anabolic Action of Wnt Inhibitor Multitargeting

Publisher

Hoboken, USA: John Wiley & Sons, Inc

Journal title

JBMR Plus, 2021-05, Vol.5 (5), p.e10462-n/a

Language

English

Formats

Publication information

Publisher

Hoboken, USA: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

ABSTRACT
Sclerostin antibody (romosozumab) was recently approved for clinical use in the United States to treat osteoporosis. We and others have explored Wnt‐based combination therapy to disproportionately improve the anabolic effects of sclerostin inhibition, including cotreatment with sclerostin antibody (Scl‐mAb) and Dkk1 antibody (Dkk1‐mAb)....

Alternative Titles

Full title

Improving Bone Health by Optimizing the Anabolic Action of Wnt Inhibitor Multitargeting

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_8bf70de22fa94fbbae843dd1f34ce38c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8bf70de22fa94fbbae843dd1f34ce38c

Other Identifiers

ISSN

2473-4039

E-ISSN

2473-4039

DOI

10.1002/jbm4.10462

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