Talin2 binds to non-muscle myosin IIa and regulates cell attachment and fibronectin secretion
Talin2 binds to non-muscle myosin IIa and regulates cell attachment and fibronectin secretion
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Talin2 is localized to large focal adhesions and is indispensable for traction force generation, invadopodium formation, cell invasion as well as metastasis. Talin2 has a higher affinity toward β-integrin tails than talin1. Moreover, disruption of the talin2-β-integrin interaction inhibits traction force generation, invadopodium formation and cell...
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Full title
Talin2 binds to non-muscle myosin IIa and regulates cell attachment and fibronectin secretion
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TN_cdi_doaj_primary_oai_doaj_org_article_8c042807ea3146289db5210edeaf6fa7
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8c042807ea3146289db5210edeaf6fa7
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-024-70866-w
