Clonal hematopoiesis with JAK2V617F promotes pulmonary hypertension with ALK1 upregulation in lung n...
Clonal hematopoiesis with JAK2V617F promotes pulmonary hypertension with ALK1 upregulation in lung neutrophils
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Pulmonary hypertension (PH) is a progressive cardiopulmonary disease characterized by pulmonary arterial remodeling. Clonal somatic mutations including
JAK2
V617F, the most frequent driver mutation among myeloproliferative neoplasms, have recently been identified in healthy individuals without hematological disorders. Here, we reveal that clo...
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Clonal hematopoiesis with JAK2V617F promotes pulmonary hypertension with ALK1 upregulation in lung neutrophils
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TN_cdi_doaj_primary_oai_doaj_org_article_8c2f8ad2f44b4473b4f42dcc6120259b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8c2f8ad2f44b4473b4f42dcc6120259b
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-26435-0
