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Capillary-associated microglia regulate vascular structure and function through PANX1-P2RY12 couplin...

Capillary-associated microglia regulate vascular structure and function through PANX1-P2RY12 couplin...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8c3b78ae6a934bf382bdde9f4a4a758d

Capillary-associated microglia regulate vascular structure and function through PANX1-P2RY12 coupling in mice

About this item

Full title

Capillary-associated microglia regulate vascular structure and function through PANX1-P2RY12 coupling in mice

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2021-09, Vol.12 (1), p.5289-13, Article 5289

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Microglia are brain-resident immune cells with a repertoire of functions in the brain. However, the extent of their interactions with the vasculature and potential regulation of vascular physiology has been insufficiently explored. Here, we document interactions between ramified CX3CR1 
+ 
myeloid cell somata and brain capillaries. We confirm...

Alternative Titles

Full title

Capillary-associated microglia regulate vascular structure and function through PANX1-P2RY12 coupling in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_8c3b78ae6a934bf382bdde9f4a4a758d

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_8c3b78ae6a934bf382bdde9f4a4a758d

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-021-25590-8

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